Natural Selection

When Dr. Curt Connors' attempt to regenerate a new arm accidentally transforms him into the Lizard, Peter, Martha, Eddie and Gwen search for a cure as Spectacular Spider-Man tries to end his criminal rampage. An overdose of a drug designed to help regenerate his missing arm has transformed Dr. Curt Connors into the crazed reptile known as the Lizard. Martha, Eddie, Peter and Gwen all look for a cure, but it's Spectacular Spider-Man who'll have to administer it. Meanwhile, though Aunt May sings the praises of Mary Jane Watson and her lovely personality, Peter remains skeptical.

Peter Parker/Spider-Man, Dr. Curt Connors/The Lizard, Harry Osborn, J. Jonah Jameson, Billy Connors, Eddie Brock, Flash Thompson, Gwen Stacy, Kenny "King" Kong, Randy Robertson, Martha Connors, Aunt May Parker, Billy Connors, Thugs

Based on the Marvel Comics classic, this new animated series focuses on the education of Peter Parker as he encounters his greatest villains, falls for his greatest loves, and faces his most dire crises, all with lots of exciting Spider-Man action. The series begins four months after a spider bite left 16-year-old Peter Parker with the superpowers that have transformed him into Spectacular Spider-Man. Still upset over the death of his uncle Ben, Peter has been working through his grief by spending the entire summer vacation taking down everyday criminals. While he revels in battling muggers, thieves and carjackers, it hasn't been much of a challenge for Peter. And while it's all been fun and fulfilling, his life as a superhero undergoes a profound change once he goes toe-to-toe with his first real super villain, the Vulture. Over 13 episodes, Peter faces a collection of rogues, such as the Lizard, Green Goblin, Kingpin and Venom, who all want to "teach that Spectacular Spider-Man a lesson!" In addition to such familiar locations as Peter's home in Forest Hills, Midtown Manhattan Magnet High School, the E.S.U. Laboratory and the Daily Bugle, the series features a host of classic Spider-Man characters, including May Parker, Dr. Otto Octavius, Harry Osborn, Gwen Stacy, Flash Thompson, Dr. Curtis Connors, Mary Jane Watson, Betty Brant, Eddie Brock and J. Jonah Jameson. As he does his best to balance the many pressures of life as a high school student with those of an emerging crime-fighter, Peter learns about love, life, family, friendship, and what it takes to translate great power to great responsibility - all in a way that young audiences can readily relate to. It's a hero's journey that has Peter growing up as he battles the forces of evil.

Working title of series: "The Amazing Spider-Man."