Plague

It's Rex's "birthday" (more accurately the anniversary of when he first joined Providence) and Six has flashbacks about how Rex first joined Providence. Back when Providence was forming, captured E.V.O.s were detained only until they were disassembled on a molecular level for study. However, Dr. Holiday, an assistant at the time, believes that studying how nanites cause mutations may one day allow for an option other than kill or contain: cure. One day, Six and his partner White Knight were called to Mexico to deal with a rampaging bio-mechanical E.V.O. only for the E.V.O. to collapse after being battered enough and revealed to be 14-year-old Rex. Rex cures a second E.V.O. right in front of Six's eyes and he brings him back to Dr. Holiday to be studied. Despite Rex being her all and more of her wildest dreams rolled into one, Six insists that they keep him under wraps for now. However, White Knight finds Rex and brings him to the head of E.V.O. Studies, Dr. Fell, in hopes that disassembling him will reveal how his curing powers work and how to cure the entire planet all in one shot.

However, Six believes that it is too big of a risk to sacrifice what they know will work for something that might or might not work. With assistance from Bobo, a recently captured E.V.O. who was holding the Kremlin hostage for caviar before his capture, Dr. Holiday is able to save Rex. However, White Knight and Six's fight had caused the E.V.O. disassembly machine to overload and destroy all the nanites in White Knight's body, but Rex is able to save White Knight's life by turning off the machine with his powers, in the process, bleaching White Knights skin and hair. Rex's curing abilities has given Providence much needed funding and White Knight is made head of Providence for his zero nanite count. Back in the present, Six gives Rex a Tanto- inscribed with the symbol of loyalty for his birthday and states that he has its twin (which was given to him for his birthday the day he found Rex) and states that it is a symbol that they are going down the same path together.

Rex, Agent Six, Noah, Dr. Holiday, Bobo Haha, White Knight, Van Kleiss, Biowulf, Breach, Skalamander, Providence Cadet Kenwyn Jones

Rex is 15, and like most 15-year-old boys, he likes cars, girls, music and sports. But unlike most 15-year-old boys, he can make his fists the size of boulders, sprout a jet pack out of his back and turn his legs into a lightning-fast motorcycle. These talents are extremely useful to Providence, a global organization chartered to fight mutant creatures known as E.V.O.s (Exponentially Variegated Organism). Rex is under their care and is their ultimate weapon.

Generator Rex takes place in the aftermath of a global accident, where microscopic machines known as nanites have merged with every living thing. For a select few, the nanites mutate their hosts into monstrous creatures called E.V.O.s.

Rex is one such E.V.O., but unlike the monsters he and Providence battle, Rex has control over his nanites. He alone has the ability to not only control these nanites- allowing him to create amazing mechanical limbs and gadgets that aid him in battle ' but also heal E.V.O.s of their mutation.

Rex's powers are incredible, and his importance to Providence and the world is undisputed. But on top of that, he just wants to be a normal teenager and must balance his adrenaline-fueled adventures with the everyday ups and downs of being 15. Rex is joined by a team of characters including his sidekick, a highly intelligent monkey named Bobo Haha who encourages Rex's mischievous side; his mentor Agent Six, so called for being the world's sixth deadliest man; the brilliant Dr. Holiday, who seems to be the only one that really understands Rex; and Noah, a regular kid and Rex's friend.

Rex's greatest threat is an E.V.O. named Van Kleiss, who with his minions called The Pack sees the nanites and resulting E.V.O.s as part of a greater plan and the future of humanity.