Sibling MineSibling Mine (2001) Season 2 Episode 107- Big Guy and Rusty the Boy Robot Cartoon Episode Guide
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- Adelaide Productions, Columbia Tri-Star Television Animation, Dark Horse Entertainment
- Columbia TriStar Domestic Television
- Big Guy and Rusty the Boy Robot Episode Guide
- Cartoon Characters: Rusty, Jo, The Big Guy, Dr. Erika Slate, Dwayne Hunter, Dr. Axel Donovan, Jenny the Monkey, Garth, Mack, General Thorton.
- Vocal Talent: Pamela Segall (Rusty, Jo), Jonathan Cook (The Big Guy), Gabrielle Carteris (Dr. Slate), Jim Hanks (Dwayne Hunter), Stephen Root (Dr. Donovan), Kathy Kinney (Jenny), Kevin Michael Richardson (Garth), M. Emmett Walsh (Mack), R. Lee Ermey (General Thorton), Tim Curry (Dr. Neugog), Kevin Schon, Jennifer Hale, Dee Bradley Baker, Nancy Cartwright, Maurice LaMarche, Victor Brandt, Sherman HowardBrian Doyle-Murray.
- Produced By Frank Squillace.
Associate Producer: Helen Kalafatic.
Co-Executive Producer: Jeff Kline.
- Series Developer: Jeff Kline.
- Creator: Frank Miller.
- Production Design: Frederick J. Gardner.
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When a botched Quark experiment brings a cycloptic creature from another dimension to Earth, it's up to Big Guy and Rusty to subdue the stampeding monster.